What does the term "vulnerable population" mean in human subjects research?

The term "vulnerable population" in human subjects research refers to groups that have a higher likelihood of experiencing coercion or undue influence. This definition recognizes that certain populations may be more susceptible to exploitation due to their circumstances, such as socioeconomic status, age, physical or mental disabilities, or lack of access to education, which may impair their ability to provide informed consent.

Identifying these populations as vulnerable necessitates implementing additional safeguards to protect them during the research process. Researchers must ensure that their participation is truly voluntary and that these individuals are not coerced into participating due to their vulnerable circumstances.

The focus on protecting vulnerable populations is crucial in ethical research practices, as it helps ensure that these groups are treated with respect and their rights are safeguarded. This definition aligns with guidelines established by ethical review boards and federal regulations, ensuring that research conducted in these contexts adheres to high ethical standards.