What must researchers do if they discover unanticipated problems during a study?

When researchers encounter unanticipated problems during a study, it is essential for them to report these findings promptly to the Institutional Review Board (IRB). The IRB is responsible for ensuring the ethical conduct of research involving human subjects, and it operates to protect participants from harm.

Reporting unanticipated problems is crucial because such issues can potentially affect the safety, well-being, or rights of participants, as well as the integrity of the research itself. By informing the IRB, researchers can receive guidance on how to address these issues, which may involve modifying study protocols, enhancing participant protections, or even halting the study until the situation is adequately assessed.

This approach not only complies with ethical and regulatory requirements but also fosters an environment of transparency and accountability in research practices. It ensures that the study remains aligned with ethical standards, prioritizing the participants' welfare throughout the research process.