What should the IRB do regarding a graduate student's project that involves prisoners as subjects?

The most appropriate course of action for the IRB regarding a graduate student's project involving prisoners as subjects would be to not approve this project because prisoners may be viewed as a vulnerable population. This context raises specific ethical concerns, particularly regarding potential coercion or undue influence since prisoners may have limited autonomy regarding participation in research.

Using prisoners as subjects simply because they are a convenient population undermines the ethical principle of respect for persons, which includes the necessity to protect vulnerable groups. It is crucial to ensure that their rights and welfare are prioritized, and that their participation in research is based on informed consent rather than convenience.

Furthermore, research involving prisoners is subject to additional federal regulations to safeguard their rights and welfare, which underscores the importance of considering the ethical implications and potential risks involved in such research. By prioritizing these protections, the IRB acts in accordance with established guidelines and the ethical framework needed for research involving vulnerable populations.