Which ethical principle relates to treating individuals with respect and allowing them to make informed choices?

The principle that relates to treating individuals with respect and allowing them to make informed choices is known as "Respect for persons." This ethical principle emphasizes the importance of recognizing the autonomy and dignity of each individual. It involves acknowledging a person's right to make decisions about their own life and participating in research voluntarily. Respect for persons also includes ensuring that individuals are provided with all the necessary information in a comprehensible manner, enabling them to make informed choices about their participation in research.

This principle is foundational in research ethics, as it reinforces the significance of informed consent, where participants are not only informed about the nature of the study but also understand the potential risks and benefits involved. It establishes the expectation that researchers will engage with participants in a manner that honors their personal values, preferences, and decision-making rights.